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Boundless LifeFull show notes: https://bengreenfieldlife.com/lotus In this episode with KJ Dhaliwal of Lotus AI, you'll hear how translating his immigrant parents' doctor visits as a child and years spent bouncing through fragmented specialty care as a teenager after a disc herniation shaped his mission to give 1

The Human Upgrade: Biohacking for Longevity & PerformanceDr. Nayan Patel reveals why oral, liposomal, and even IV glutathione never actually reach your cells, and the transdermal delivery breakthrough that finally does.

Huberman LabIn this Huberman Lab Essentials episode, I explain the biology, symptoms and types of bipolar disorder (sometimes called bipolar depression), a condition characterized by extreme, maladaptive shifts in energy, mood and perception. I describe the diagnostic criteria that distinguish bipolar I from bipolar II, including mania and hypomania and the different patterns of mood cycling. I discuss the remarkable history and discovery of lithium and how it works, in part by reducing inflammation, providing neuroprotection and supporting the interoceptive neural circuits affected in bipolar disorder. I also cover talk therapies, electroconvulsive therapy and nutraceuticals such as omega-3 fatty acids and inositol, and I explore the intriguing relationship between mood disorders and creativity. This episode should interest anyone who has or knows someone with bipolar disorder, as well as those interested in how the brain balances mood, energy and focus. Read the show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman BetterHelp: https://betterhelp.com/huberman Eight Sleep: https://eightsleep.com/huberman Timestamps (00:00:00) Bipolar Disorder (00:01:09) Bipolar I; Manic Episode Symptoms (00:05:00) Bipolar II, Hypomania; Depressive Episodes & Cycling (00:09:00) Sponsor: BetterHelp (00:10:09) Lithium Discovery, Dr. John Cade, Uric Acid (00:12:14) Lithium Urate & Guinea Pigs, Control Experiments (00:13:19) Lithium Salts Paper, Toxicity & Monitoring (00:15:40) How Lithium Works: Inflammation & Neuroprotection (00:16:50) Exteroception vs. Interoception, Neural Circuit Atrophy (00:19:04) Sponsor: AG1 (00:20:29) Drug vs. Talk Therapies (00:20:40) Cognitive Behavioral Therapy, Interpersonal & Social Rhythm Therapy (00:22:30) Electroconvulsive Therapy (ECT), Treatment-Resistant Depression (00:24:07) Caution: Rely on Prescribed Treatment, Suicide Risk (00:24:59) Tool: Lifestyle Support, Sleep, Exercise, Nutrition & Sunlight (00:26:05) Tool: Inositol & Omega-3 Fatty Acids, Fish Oil Study (00:29:53) Sponsor: Eight Sleep (00:31:10) Creativity & Mood Disorders, Eminent Individuals Study (00:34:00) Recap & Key Takeaways Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

The Human Upgrade: Biohacking for Longevity & PerformanceDr. Peter McCullough traces the spike protein's origins to 2015 gain-of-function research, explains why it can persist in the body for years after vaccination, and breaks down the science behind clearing it, the suppression of early COVID treatments, and what he'd change if he ran HHS.

Huberman LabDr. Alan Castel, PhD, is a professor of psychology at the University of California, Los Angeles (UCLA) and one of the world's foremost experts on human memory and cognitive aging. We discuss what science actually tells us about how to improve our learning ability and memory at any age. We also discuss how memory works, why all planning and imagination about the future is based on the past, false memories, and how to leverage curiosity, emotion, and self-testing retrieval practice to stamp in memories for the long term. We discuss what "superagers"—people who actually improve their cognitive capacity with age—do differently than everyone else. This episode is for anyone interested in the science of memory and tools to maintain and improve your memory across the lifespan. Thank you to our sponsors AG1: https://drinkag1.com/huberman Wealthfront*: https://wealthfront.com/huberman Helix Sleep: https://helixsleep.com/huberman Function: https://functionhealth.com/huberman Lingo: https://hellolingo.com/huberman Timestamps (00:00:00) Dr. Alan Castel (00:02:41) What Is Memory?, Reconstruction & Metacognition (00:04:49) Mnemonics, Remembering Names & Deeper Learning (00:08:22) The Penny & Apple Logo, Noticing vs Seeing, Learning Through Mistakes (00:10:43) Sponsors: Wealthfront & Helix (00:14:05) Neuroplasticity, Frustration, Curiosity & Mindset (00:17:42) Maintaining vs Learning New Things, Habits, Novelty & Emotional Memory (00:24:28) "Mental Photographs," Photo-Taking & Imagining the Future (00:29:28) Eyewitness Memory, the Ronald Cotton Case, Confidence vs Accuracy (00:35:07) Medium-Term & Prospective Memory, Hotel Fire Exits (00:40:28) Sponsor: AG1 (00:41:47) When Habits Turn Lethal, Aviation & Human Error (00:49:01) Why Memory Changes With Age; Alzheimer's & the Nun Study (00:52:34) Exercise & Hippocampal Volume, Falls & Balance (00:57:14) SuperAgers & Athletes; Regret, Balance & Being Driven (01:12:08) Sponsor: Function (01:13:45) Age Stereotypes, Subjective Age & Positive Age Beliefs (01:20:02) Goals & Plans, Scams; Anterior Midcingulate Cortex & SuperAgers (01:26:23) Culture, Resilience, Blue Zones & COVID (01:29:18) Adversity, the Positivity Effect & Intergenerational Learning (01:36:31) Sponsor: Lingo (01:38:00) Limitations & Purpose; Time, Family & Connection (01:44:58) Deliberately Building Memories; the ABCs of Successful Aging (01:51:02) Following Your Interests; Castel's Path & Older Adults (01:57:16) Mental Simulations, Curiosity Studies & Selectivity (02:01:19) Socioemotional Selectivity Theory; Steve Jobs & Lifespan (02:07:10) The Secret to Successful Aging; State vs Trait Curiosity (02:11:04) Scams & AI Voice Cloning (02:14:31) John Wooden, Wisdom, Love & Balance (02:17:41) Learning Through Mistakes; Does the Brain Get Better With Age? (02:25:00) Conclusion, Better With Age (02:26:00) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures *This experience may not be representative of other Wealthfront clients, and there is no guarantee of future performance or success. Experiences will vary. Andrew Huberman receives cash compensation from Wealthfront Brokerage for paid testimonials in his podcast, creating a conflict of interest. The Cash Account, which is not a deposit account, is offered by Wealthfront Brokerage LLC, member FINRA/SIPC. Wealthfront Brokerage is not a bank. The base APY is 3.30% on cash deposits as of January 30, 2026, is representative, subject to change, and requires no minimum. If eligible for the overall boosted rate of 4.05% offered in connection with this promo, your boosted rate is also subject to change if the base rate decreases during the 3 month promo period. Additional terms and conditions apply, which can be found on Wealthfront.com/Huberman. Funds in the Cash Account are swept to program banks, where it earns the variable APY. Same-day withdrawal or instant payment transfers may be limited by destination institutions, daily transaction caps, and by participating entities such as Wells Fargo, the RTP® Network, and FedNow® Service. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer. Investment advisory services are provided by Wealthfront Advisers LLC, an SEC-registered investment adviser. Securities investments: not bank deposits, bank-guaranteed or FDIC-insured, and may lose value. Learn more about your ad choices. Visit megaphone.fm/adchoices

The Peter Attia DriveView the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Gayatri Devi is a nationally recognized neurologist specializing in memory disorders, including Alzheimer's disease and related dementias. In this episode, Gayatri expl

The Human Upgrade: Biohacking for Longevity & PerformanceA Japanese village's daily breakfast of natto — rich in spermidine — triggers the Nobel Prize-winning cellular repair process of autophagy, reversing biological aging within 72 hours when combined with proper dosing, exercise, sleep, and diet.

Boundless LifeFull show notes: https://bengreenfieldlife.com/tectonpodcast In this episode with Dr. Mike Chesne, founder of Tecton Ketones™, you'll hear how a traumatic brain injury sustained in combat led him from Army Special Forces medic to ketone biochemist, and why he eventually built what he believes is a m

The Human Upgrade: Biohacking for Longevity & PerformanceJordan Harbinger joins Dave Asprey to share how he talked his way out of two kidnappings and breaks down the psychology-driven systems — calendar blocking, pain-point habit hacks, and relationship-building — he uses to stay productive and charming under pressure.

Boundless LifeFull show notes: https://bengreenfieldlife.com/502 In this solosode, you'll explore how to make peace with tinnitus after acoustic trauma, including the half dozen different root causes that can drive it and the specific supplements and technologies with research behind them, why cardiovascular fitn

The Human Upgrade: Biohacking for Longevity & PerformanceDave Asprey sits down with Dr. David Perlmutter to explore how brain inflammation and microglial dysfunction drive Alzheimer's, Parkinson's, and other neurodegenerative conditions — debunking the amyloid hypothesis along the way and examining emerging treatments like GLP-1 drugs, 40 hertz light therapy, and lifestyle interventions.

Huberman LabIn this Huberman Lab Essentials episode, I explain the biology and psychology of obsessive-compulsive disorder (OCD) and describe the neural circuitry behind repetitive "thought-action loops," including why compulsive actions actually strengthen the underlying obsessions rather than relieve them. I discuss the most effective treatments for OCD, including exposure-based cognitive behavioral therapy and SSRIs, and explain what the research shows about how these compare when used alone versus together. Finally, I describe a specific clinical protocol in which patients are guided into states of anxiety while learning to suppress compulsive responses, retraining the brain to break the OCD cycle. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman Rorra: https://rorra.com/huberman Timestamps (00:00:00) Obsessive-Compulsive Disorder (OCD) (00:00:11) OCD Prevalence & Impact, Obsessions & Compulsions (00:01:54) Categories: Checking, Repetition & Order; Contamination & Disgust (00:04:30) Anxiety, Fear (00:05:20) Sponsor: AG1 (00:06:40) Genetic Component of OCD (00:08:45) Neural Circuitry, Cortex, Striatum, Thalamus (00:10:16) Cortico-Striatal-Thalamic Loop; Imaging Studies, SSRIs (00:14:30) Sponsor: Eight Sleep (00:16:00) Diagnosis, Yale-Brown Obsessive Compulsive Scale (Y-BOCS) (00:18:00) Y-BOCS Categories, Identifying the Core Fear (00:19:30) Tool: Cognitive Behavioral Therapy (CBT) & Exposure Therapy (00:21:39) Anxiety Tolerance, Interrupting the Compulsion (00:23:23) Dr. Helen Blair Simpson, Ritual Prevention, Exposure Sessions (00:25:18) CBT vs Placebo vs SSRIs (00:26:30) Sponsor: Rorra (00:28:07) SSRIs & Serotonin System; Psychiatry & Causality (00:29:13) Cannabis, CBD & OCD; Transcranial Magnetic Stimulation (TMS) (00:31:48) Mindfulness Meditation, Holistic Treatments, NIH (00:33:40) Nutraceuticals, Inositol; Recap & Conclusion Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices